LTA Protein (AA 35-205)

Catalog No. ABIN7504984

This Recombinant LTA protein is produced in Escherichia coli (E. coli).

Quick Overview for LTA Protein (AA 35-205) (ABIN7504984)

Target: LTA (Lymphotoxin-alpha (LTA))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 35-205

Sequence: Leu35-Leu205

Characteristics: A DNA sequence encoding the Human TNF β/LTA Protein(P01374)(Leu35-Leu205)was expressed with a polyhistidine tag at the N-terminus.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 12 months

Target Details

Target: LTA (Lymphotoxin-alpha (LTA))

Alternative Name: TNF beta

Target Type: Chemical

Background:

Abbreviation: TNF β,LTA

Target Synonym: Lymphotoxin-alpha,LT-alpha,TNF-beta,Tumor necrosis factor ligand superfamily member 1,LTA,TNFB,TNFSF1

Background: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM (PubMed:9462508). In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.

Molecular Weight:

Calculated MW: 18.7 kDa

Observed MW: 19 kDa

UniProt: P01374

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process